Intermediates & APIs :
Amrisha began manufacturing operations in 2008. Our expertise has helped us develop a wide portfolio of intermediates and APIs. Our teams’ commitment, state of the art infrastructure, and flexibility in bringing products to the market quickly and economically have won us customer confidence in this short period of time. We have emerged as a trusted supplier of value-added advanced intermediates and APIs.
List of Intermediates & Active Pharmaceutical Ingredients :
S.No | Product Name | Synonyms | End Product | Therapeutic Activity | CAS No. | Molecular Structure |
---|---|---|---|---|---|---|
1 | (1S,4R)-(4-Aminocyclopent-2-enyl) methanol hydrochloride MF: C6H12ClNO; M. Wt: 149.62 |
2-Cyclopentene-1-methan-ol, 4-amino hydrochloride (1S,4R) |
Abacavir | Antiviral (HIV) | 168960-19-8 | |
2 | (1S-cis)-4-Amino-2- cyclopentene-1-methan-ol D-hydrogen tartrate MF: C10H17NO7; M. Wt: 263.24 |
(1S,4R)-4-Amino-2-cyclopentene-1-methanol (2S,3S)-2,3-dihydroxy butanedioate | Abacavir | Antiviral (HIV) | 229177-52-0 | |
3 | N-(2-Amino-4,6- dichloropyrimidin-5-yl) formamide MF: C5H4Cl2N4O; M. Wt: 207.02 |
2-Amino-4,6-dichloro-5- pyrimidinyl formamide |
Abacavir | Antiviral (HIV) | 171887-03-9 | |
4 | 4-Hydrazinobenzene-1-sulfonamide hydrochloride MF: C6H10ClN3O2S; M. Wt: 223.68 |
Benzenesulfonamide,4-hydrazino-monohydrochloride; Benzenesulfonamide, p- hydrazino-monohydrochlorid; |
Celicoxib | Anti-inflammatory | 17852-52-7 | |
5 | (1S,5R)-1-Phenyl-3-oxabicyclo[3.1.0] hexan- 2-one MF: C11H10O2; M. Wt: 174.20 |
2-Oxo-1-phenyl-3-oxabicyclo[3.1.0]-hexane | Milnacipran | Antidepressant | 63106-93-4 | |
6 | 1-Cyclopropyl-2-fluoro- benzyl ketone MF: C11H11FO; M. Wt: 178.20 |
1-Cyclopropyl-2-(2-Fluoro- phenyl)-ethanone; Cyclo- propyl-2-fluorobenzyl ketone |
Prasugrel | Platelet Inhibitor | 150322-73-9 | |
7 | 2-Bromo-2-(2-fluoro- phenyl)-1-cyclopropyl- ethanone MF: C11H10BrFO; M. Wt: 257.10 |
Ethanone, 2-bromo-1-cyclo- propyl 2-(2-fluorophenyl) |
Prasugrel | Platelet Inhibitor | 204205-33-4 | |
8 | 3-Piperazinyl-1,2- benzisothiazole hydrochloride MF: C11H14ClN3S; M. Wt: 255.77 |
1-(1,2-Benzisothiazol-3-yl) piperazine hydrochloride; 3-Piperazinobenzisothiazole hydrochloride; 3-(1-Piperazinyl)-1,2-benz- isothiazole hydrochloride |
Ziprasidone | Anti Psychotic | 87691-88-1 | |
9 | 3-(1-Piperazinyl)-1,2- benzisothiazole MF: C11H13N3S; M. Wt: 219.31 |
N-(3-Benzisothiazolyl) piperazine; 3-(Piperazin-1-yl) benzoisothiazole |
Ziprasidone | Anti Psychotic | 87691-87-0 | |
10 | 3-Chloro-1,2- benzisothiazole MF: C7H4ClNS; M. Wt: 169.63 |
3-Chlorobenzoisothiazole | Ziprasidone | Anti Psychotic | 7716-66-7 | |
11 | 4′-Bromomethyl-2- biphenylcarbonitrile MF: C14H10BrN; M. Wt: 272.14 |
2-Cyano-4′-bromomethyl biphenyl; 4′-(Bromomethyl)- 2-cyanobiphenyl |
Valsartan Losartan Irbesartan |
Antihypertensive | 114772-54-2 | |
12 | 5-[2-(4′-Methyl biphenyl)] tetrazole MF: C14H12N4; M. Wt: 236.27 |
5-(4′-Methyl[1,1′-biphenyl]-2-yl)-2H-tetrazole; 5-(4′-Methyl-2-biphenyl) tetrazole; Losartan EP Impurity E Losartan Methyl Impurity; Candesartan Methyl Impurity Irbesartan Methyl Impurity |
Valsartan Losartan Irbesartan |
Antihypertensive | 120568-11-8 | |
13 | 5-(4′-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole MF: C33H26N4; M. Wt: 478.59 |
5-(4′-Methyl-[1,1′-biphenyl]-2-yl)-1-trityl-1H-tetrazole; N-(Triphenylmethyl)-5-(4′- methylbiphenyl-2-yl)tetrazole |
Valsartan Losartan Irbesartan |
Antihypertensive | 124750-53-4 | |
14 | 5-(4′-Bromomethyl-1,1′-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole MF: C33H25BrN4; M. Wt: 557.48 |
N-(Triphenylmethyl)-5-(4′- bromomethylbiphenyl-2-yl-) tetrazole; 2′-(N-Trityltetrazol- 5-yl)biphenyl-4-yl]methyl bromide; 1-Triphenylmethyl- 5-[4′-(bromomethyl) biphenyl -2-yl]tetrazole |
Valsartan Losartan Irbesartan |
Antihypertensive | 124750-51-2 | |
15 | (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine MF: C9H15NOS; M. Wt: 185.29 |
(S)-3-(Dimethylamino)-1- (2-thienyl)-1-propanol |
Duloxetine | Osteoarthiritis & Musculoskeletal Pain |
132335-44-5 | |
16 | 3-Dimethylamino-1-(2- thienyl)-1-propanone hydrochloride MF: C9H14ClNOS; M. Wt: 219.73 |
3-(Dimethylamino)-1- (thiophen -2-yl)propan-1-one hydrochloride; 2-Thienyl- 2-dimethylaminoethyl ketone HCl |
Duloxetine | Antidepressant | 5424-47-5 | |
17 | (S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propan- amine oxalate MF: C21H23NO5S; M. Wt: 401.47 |
(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine oxalate | Duloxetine | Antidepressant | 132335-47-8 | |
18 | (+)-(S)-N-methyl-3-(1-naphthyloxy)-2-thiophenepropyl amine oxalate MF: C21H23NO5S; M. Wt: 401.47 |
(S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl) propan-1-amine oxalate; Duloxetine oxalate |
Duloxetine | Antidepressant | Not available | |
19 | (S)-3-(Methylamino)-1-(2-thienyl)-1-propanol MF: C8H13NOS; M. Wt: 171.26 |
(S)-2-[3-(Methylamino)-1- hydroxypropyl]thiophene; (S)-3-(Methylamino)-1-(thio- phen-2-yl)propan-1-ol |
Duloxetine | Osteoarthiritis & Musculoskeletal Pain |
116539-55-0 | |
20 | 5-(4-Fluorophenyl)-5- oxopentanoic acid MF: C11H11FO3; M. Wt: 210.20 |
4-(4-Fluorobenzoyl)butyric acid;4-(4-Fluorobenzoy)-1- butanoic acid; 4-Fluorophenyl -5-oxobutyric Acid |
Ezetimibe | Anti-cholesterol | 149437-76-3 | |
21 | 4{(E)-[(4-Fluorophenyl)imino]methyl}phenol MF: C13H10FNO; M. Wt: 215.23 |
4-Fluoro-N-(4-hydroxy phenyl) methylene-benzen- amine; 4-{[(4-Fluorophenyl) imino]methyl}phenol |
Ezetimibe | Anti-cholesterol | 3382-63-6 | |
22 | N-(4-(Benzyloxy)benz ylidene)-4-fluoroaniline MF: C20H16FNO; M. Wt: 305.35 |
4-Benzyloxybenzylidene-(4- fluoro)aniline; 4,4-Benzyloxy benzylidene P- fluoroaniline; N-(4-(Benzyloxy)benz ylidene)-4-fluoroaniline |
Ezetimibe | Anti-cholesterol | 70627-52-0 | |
23 | 6-Methoxy-2- napthaldehyde MF: C12H10O2; M. Wt: 186.21 |
6-Methoxynaphthalene- 2-carbaldehyde |
Nabumetone | Anti-Inflammatory | 3453-33-6 | |
24 | 2-Bromo-6-methoxy naphthalene MF: C11H9BrO; M. Wt: 237.09 |
6-Bromo-2-methoxy napthalene; Naproxen EP IMpurity N |
Nabumetone | Anti-Inflammatory | 5111-65-9 | |
25 | 3-(N-Benzyl-N-methyl amino)-1-phenylpropan -1-one hydrochloride MF: C17H20ClNO; M. Wt: 289.80 |
3-(N-Benzyl-N-methylamino) propiophenone hydrochloride | Fluoxetine | Antidepressant | 5409-62-1 | |
26 | 3-Hydroxy-N-methyl-3-phenyl-propylamine MF: C10H15NO; M. Wt: 165.23 |
Alpha-[2-(Methylamino)ethyl]benzyl alcohol | Fluoxetine | Antidepressant | 42142-52-9 | |
27 | 2,3:4,5-Di-O- isopropylidene-β-D- fructopyranose MF: C12H20O6; M. Wt: 260.28 |
Diacetonefructose; 1,2,4,5- Di-O-isopropylidene-β-D- fructopyranose |
Topiramate | Anti-convulsant | 20880-92-6 | |
28 | 3-(Dimethylamino)-1- phenylpropan-1-one hydrochloride MF: C11H16ClNO; M. Wt: 213.70 |
2-Benzylethyldimethylamine hydrochloride; Beta-(Di- methylamino)propiophenone hydrochloride |
Fluoxetine Atomoxetine |
Anti-depressant | 3506-36-3 | |
29 | 3-(Dimethylamino)-1- phenylpropan-1-ol MF: C11H17NO; M. Wt: 179.26 |
N,N-Dimethyl-3-phenyl-3- hydroxypropylamine |
Fluoxetine Atomoxetine |
Anti-Depressant | 36296-95-4 | |
30 | 3-(4-(Trifluoromethyl) phenoxy)-N,N-dimethyl-3-phenylpropan-1- amine MF: C18H20F3NO; M. Wt: 323.35 |
N,N-Dimethyl-gamma-[4- (trifluoromethyl)phenoxy] benzenepropanamine; N,N- Dimethyl-gamma-(4-trifluoromethylphenoxy)phenylpropyl amine |
Fluoxetine Atomoxetine |
Anti-depressant | 56225-81-1 | |
31 | 3-(4-(Trifluoromethyl) phenoxy)-N,N-dimethyl-3-phenylpropan-1- amine oxalate salt MF: C20H22F3NO5; M. Wt: 413.0 |
N-methyl fluoxetine oxalate salt;N,N-Dimethyl-[4-trifluoro methyl)phenoxy]benzene propanamine oxalate salt |
Fluoxetine Atomoxetine |
Anti-depressant | Not available | |
32 | Montelukast MF: C35H36ClNO3S; M. Wt: 586.18 |
(R-(E))-1-(((1-(3-(2-(7- Chloro-2-quinolinyl)ethenyl) phenyl)-3-(2-(1-hydroxy-1- methylethyl)phenyl)propyl) thio) methyl)cyclopropane acetic acid; Montelukast acid |
Montelukast | Antiasthmatic | 158966-92-8 | |
33 | Montelukast tert-butylamine salt MF: C39H49ClN2O3S; M. Wt: 661.34 |
(R,E)-2-(1-((1-(3-(2-(7- Chloroquinolin-2-yl) vinyl) phenyl)-3-(2-(2-hydroxy propan-2-yl) phenyl)propyl thio)methyl)cyclopropyl) acetic acid t-butylamine salt |
Montelukast | Antiasthmatic | Not available | |
34 | Montelukast sodium MF: C35H35ClNNaO3S; M. Wt: 608.17 |
(R,E)-2-(1-((1-(3-(2-(7- Chloroquinolin-2-yl) vinyl) phenyl)-3-(2-(2-hydroxy propan-2-yl) phenyl)propyl thio)methyl)cyclopropyl) acetic acid sodium salt |
Montelukast | Antiasthmatic | 151767-02-1 | |
35 | 4′-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl) methyl]-1,1′-biphenyl-2-carbonitrile MF: C22H22ClN3O; M. Wt: 379.88 |
2-(4-{[2-Butyl-4-chloro-5- (hydroxymethyl)imidazolyl] methyl} phenyl)benzene carbonitrile |
Losartan | Antihypertensive | 114772-55-3 | |
36 | (1-((2′-(2H-tetrazol-5- yl)biphenyl-4-yl) methyl)-2-butyl-4- chloro-1H-imidazol- 5-yl) methanol MF: C22H23ClN6O; M. Wt: 422.91 |
Losartan; 2-Butyl-4-chloro-5-(hydroxymethyl)-1-[(2′-(1H- tetrazol-5-yl)-1,1′-biphenyl- 4-yl)methyl]-1H-imidazole |
Losartan | Antihypertensive | 114798-26-4 | |
37 | L-Valine methyl ester hydrochloride MF: C6H14ClNO2; M. Wt: 167.63 |
(S)-Methyl 2-amino-3-methyl-butanoate hydrochloride | Valsartan | Antihypertensive | 6306-52-1 | |
38 | N-[(2′-Cyanobiphenyl-4-yl)methyl]-(L)-valine methyl ester hydrochloride MF: C20H23ClN2O2; M. Wt: 358.86 |
N-[(2′-Cyano[1,1’biphenyl]-4-yl)methyl]-methyl ester L-valine mono hydrochloride |
Valsartan | Antihypertensive | 482577-59-3 | |
39 | L-Valine benzyl ester p-toluenesulfonate salt MF: C19H25NO5S; M. Wt: 379.47 |
L-Valine benzyl ester 4-toluenesulfonate |
Valsartan | Antihypertensive | 16652-76-9 | |
40 | N-[(2′-(1-Triphenyl methyl) tetrazole-5-yl) biphenyl)-4-yl) methyl] -L-valine benzyl ester oxalate salt MF: C47H43N5O6; M. Wt: 773.87 |
Valsartan | Antihypertensive | Not available | ||
41 | 4′-Methyl-2-biphenyl carboxylic acid MF: C14H12O2; M. Wt: 212.24 |
4′-Methyl[1,1′-biphenyl]-2- carboxylicacid-2-(p-tolyl) benzoic acid |
Telmisartan | Antihypertensive | 7148-03-0 | |
42 | 4′-Methylbiphenyl-2- carboxylic acid methyl ester MF: C15H14O2; M. Wt: 226.27 |
Methyl 4′-methylbiphenyl-2- carboxylate |
Telmisartan | Antihypertensive | 114772-34-8 | |
43 | Methyl 4′-bromomethyl biphenyl-2-carboxylate MF: C15H13BrO2; M. Wt: 305.17 |
4′-Bromomethyl-(1,1′- biphenyl)-2-carboxylic acid methyl ester; Methyl 2-[4- (bromomethyl)phenyl] benzoate |
Telmisartan | Antihypertensive | 114772-38-2 | |
44 | 4-(3,4-Dichlorophenyl)-3,4-dihydro-1-(2H)- napthalone MF: C16H12Cl2O; M. Wt: 291.17 |
4-(3,4-Dichlorophenyl)-1- tetralone;4-(3,4-Dichloro- phenyl)-alpha-tetralone |
Sertraline | Antidepressant | 79560-19-3 | |
45 | 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N- methyl-1- naphthalenimine MF: C17H15Cl2N; M. Wt: 304.21 |
N-(4(3,4-Dichlorophenyl)-3,4-dihydro-1(2H)naphthalidene) methanamine | Sertraline | Antidepressant | 79560-20-6 | |
46 | 4-Hydrazino-N-methyl-benzenemethane sulfonamide monohydrochloride MF: C8H14ClN3O2S; M. Wt: 251.73 |
N-Methyl-4-diazanylsulfa- benzamide hydrochloride; 4-Hydrazinyl-N-Methyl benzenemethanesulfonamide Hydrochloride |
Sumatriptan | Antimigraine | 88933-16-8 | |
47 | Sodium 4-chloro-1- hydroxybutane sulfonate MF: C4H8ClNaO4S; M. Wt: 210.61 |
4-Chloro butyraldehyde sodium bisulphite adduct |
Sumatriptan | Antimigraine | 54322-20-2 | |
48 | 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1- hydroxybutyl)-3- (hydroxymethyl)benzo- nitrile hydrochloride MF: C20H24ClFN2O2; M. Wt: 378.87 |
Benzonitrile, 4-[4-(dimethyl amino)-1-(4-fluorophenyl)-1- hydroxybutyl]-3-(hydroxy methyl) hydrochloride |
Citalopram | Antidepressant | 717133-25-0 | |
49 | (-)4-(4-Dimethylamino)-1-(4-fluorophenyl)-1- (hydroxybuty)-3- hydroxymethyl)-benzo- nitrile hemi D-(+)-di- p-toloyltartaric acid salt MF: 2(C20H23FN2O2). C20H18O8; M. Wt: 1071.17 |
(S)-4-[4-(Dimethylamino)-1- (4-fluorophenyl)-1-hydroxy- butyl]-3-(hydroxymethyl) benzonitrile (2S,3S)-2,3-bis [(4-methylbenzoyl) oxy] butanedioate |
Escitalopram | Antidepressant | 128173-53-5 | |
50 | N-Carbobenzyloxy- L-valine MF: C13H17NO4; M. Wt: 251.28 |
CBZ-L-Valine; N-CBZ-L-VALINE; Z-VAL; Z-Valine |
Valacyclovir | Antiviral | 1149-26-4 | |
51 | (2R,5S)-(1R,2S,5R)-2- isopropyl-5-methyl cyclohexyl-5-(4-amino- 2-oxopyrimidin-1(2H)- yl)-1,3-oxathiolane-2- carboxylate (CME) MF: C18H27N3O4S; M. Wt: 381.49 |
(1R,2S,5R)-Menthyl-(2R,5S)-5-(4-amino-2-oxo-2H- pyrimidin-1-yl)-[1,3]oxa- thiolane-2-carboxylic acid; Lamivudine intermediate (CME) |
Lamivudine | Antiviral (HIV) | 147027-10-9 | |
52 | (2R,5S)-(1R,2S,5R)-2- isopropyl-5-methyl cyclohexyl 5-(4-amino- 5-fluoro-2-oxopyrimidin -1(2H)-yl)-1,3-oxa- thiolane-2-carboxylate (FCME) MF: C18H26FN3O4S; M. Wt: 399.49 |
(2R,5S)-5-(4-amino-5-fluoro-2-oxo-2H-pyrimidin-1-yl)- [1,3]-oxathiolane-2- carboxylic acid, 2S-isopropyl-5R-methyl-1R-cycIohexyl ester; Emtricitabine intermediate (FCME) |
Emtricitabine | Antiviral (HIV) | 764659-72-5 | |
53 | Methyl alpha-bromo-2- chlorophenylacetate MF: C9H8BrClO2; M. Wt: 263.52 |
Methyl 2-bromo-2-(2-chloro phenyl) acetate; α-Bromo-2- chlorobenzene acetic acid methyl ester |
Clopidogrel | Platelet Inhibitor | 85259-19-4 | |
54 | (S)-(+)-3-Hydroxy tetrahydrofuran MF: C4H8O2; M. Wt: 88.11 |
(S)-Tetrahydro-3-furanol; (3S)-Tetrahydrofuran-3β-ol |
Fosamprenavir Amprenavir Afatinib |
Protease inhibitor | 86087-23-2 | |
55 | 4-(4-Fluorophenyl)-6- isopropyl-2-[(N-methyl -N-methyl sulfonyl) amino] pyrimidine carboxaldehyde MF: C9H15NOS; M. Wt: 351.39 |
4-(4-Fluorophenyl)-6-iso- propyl-2-[(N-methyl-N- methyl sulfonyl) amino] pyrimidinyl-5-yl -formyl |
Rosuvastatin | Anti-cholesterol | 147118-37-4 | |
56 | 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide MF: C26H24FNO3; M. Wt: 417.47 |
2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl ethyl]-4-methyl-3- oxo-pentanoic acid phenylamide; Atorvastatin Intermediate 2 |
Atorvastatin | Anti-cholesterol | 125971-96-2 | |
57 | 3-(Trifluoromethyl) cinnamic acid (Predominantly trans) MF: C10H7F3O2; M. Wt: 216.15 |
(E)-3-(3-(Trifluoromethyl) phenyl) acrylic acid; m-(Trifluoromethyl) cinnamic acid |
Cinacalcet | Antihyper parathyroidism (Anti HPT) |
779-89-5 | |
58 | N-[2-Amino-4-chloro-6-[[(1R,4S)-4-(hydroxy- methyl)-2-cyclopenten -1-yl]amino]-5- pyrimidinyl]formamide MF: C11H14ClN5O2; M. Wt: 283.71 |
(1R-cis)-N-[2-amino-4-chloro-6-[[4-(hydroxymethyl)-2- cyclopenten-1-yl]amino]-5- pyrimidinyl]-formamide |
Abacavir | Antiviral (HIV) | 171887-04-0 | |
59 | (1S,4R)-4-(2-Amino-6- chloro-9H-purin-9-yl)- 2-cyclopentene-1- methanol hydrochloride MF: C11H13Cl2N5O; M. Wt:302.16 |
[(1S,4R)-4-(2-Amino-6- chloro-9H-purin-9-yl) cyclopent-2-enyl] methanol hydrochloride; Abacavir intermediate C |
Abacavir | Antiviral (HIV) | 172015-79-1 |